Downloads:

• Full setup

  MD5-Hash	SHA256-Hash
  5da0e1b370941f5e6628401cdd0dce1e	092ee97cb65f2259542409982e1c9041a8d58291fe5c7daed371d9b538642624

• ospsuite R package

• Gene expression database (human)

Release Notes for the Open Systems Pharmacology Software Suite 11 Update 3

New features

This is a pure bug fix and performance improvement release. No new features implemented.

Fixed issues and Improvements

PK-Sim

• Observed data mappings get duplicated when cloning a simulation
• Changing the transport direction in the expression profile is not applied in the simulation.
• Projects created with version $\leq 10$ are sometimes not exported correctly to a snapshot with version $\geq 11$.
• Error displaying PK analysis in population simulation in some scenarios
• Create Individual: wrongly memorized age
• Unit of t_1/2 in individual enzyme expression not updated when changing unit in expression profile
• Concentration parameter must be created with CanBeVaried = false

PK-Sim and MoBi

• Parameter identification: significant performance improvement when dealing with large number of observed data sets
• Performance improvement when handling charts with many displayed curves
• Crash in cloned parameter identification after project save/load
• getAllParametersMatching() should append |* to each path that ends with |**.

New release of the ospsuite R package

No new features. New release only due to the changes in the embedded OSP libraries.